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45 Minute Lower Body Workout: For Strength & Muscle-Building

Infographic of 45 minute lower body workout set and reps.

If you want stronger legs, bigger quads, rounder glutes, and powerful hamstrings, this 45 minute lower body workout is designed to deliver maximum results in minimal time. Whether your goal is hypertrophy, fat loss, athletic performance, or overall strength, this structured leg day routine combines compound lifts, targeted accessory work, and conditioning to fully challenge your lower body.

This SEO-optimized guide breaks down everything you need: warm-up, workout structure, sets, reps, tempo, rest periods, and progression strategies. By the end, you’ll have a complete, science-backed plan you can use weekly to build serious lower body strength and size.

Why a 45 Minute Lower Body Workout Is Ideal

A well-designed 45 minute lower body workout hits the sweet spot between volume and intensity. You get enough stimulus for muscle growth without spending hours in the gym.

Benefits of a 45 Minute Leg Workout

  • Maximizes training intensity
  • Efficient for busy schedules
  • Encourages progressive overload
  • Supports fat loss and metabolic conditioning
  • Reduces overtraining risk

Training legs properly requires effort and structure. With strategic rest times and compound-focused programming, 45 minutes is more than enough to spark growth.

Muscle Groups Targeted in This Lower Body Workout

A complete leg workout must train:

1. Quadriceps

Front thigh muscles responsible for knee extension.

2. Hamstrings

Back thigh muscles responsible for hip extension and knee flexion.

3. Glutes

Primary hip extensors and essential for power, aesthetics, and performance.

4. Calves

Responsible for ankle stability and explosive movement.

5. Core Stabilizers

Bracing during squats and lunges activates the abs and lower back.

This 45 minute lower body workout strategically hits each muscle group with both compound and isolation exercises.

45 Minute Lower Body Workout Plan Overview

Workout Structure:

  • 5–7 minute dynamic warm-up
  • 3 compound strength movements
  • 2 accessory hypertrophy exercises
  • 1 metabolic finisher

Total Time: 45 Minutes
Equipment Needed: Barbell or Dumbbells (can modify for either)

Dynamic Warm-Up (5–7 Minutes)

Warming up increases blood flow, improves mobility, and reduces injury risk.

Perform:

  • Bodyweight squats – 2 x 15
  • Walking lunges – 2 x 10 each leg
  • Glute bridges – 2 x 15
  • Leg swings (front & side) – 15 each
  • Light goblet squat – 1 x 12

Focus on controlled movements and activating your glutes.

Main Workout: 45 Minute Lower Body Routine

Exercise 1: Barbell Back Squat (Strength Focus)

Sets: 4
Reps: 6–8
Rest: 90 seconds

The back squat is the king of lower body exercises. It targets quads, glutes, hamstrings, and core simultaneously.

Coaching Cues:

  • Keep chest tall
  • Push knees outward
  • Drive through heels
  • Hit parallel or below

If you don’t have a barbell, substitute heavy dumbbell goblet squats.

Exercise 2: Romanian Deadlift (Hamstring & Glute Builder)

Sets: 3
Reps: 8–10
Rest: 75 seconds

The Romanian deadlift emphasizes the posterior chain.

Focus On:

  • Hinging at hips
  • Slight knee bend
  • Stretch in hamstrings
  • Controlled eccentric (3 seconds down)

This movement balances quad-dominant squats and builds powerful glutes.

Exercise 3: Bulgarian Split Squat (Unilateral Strength)

Sets: 3
Reps: 8–10 each leg
Rest: 60 seconds

Single-leg training corrects imbalances and increases glute activation.

Tips:

  • Keep torso slightly forward
  • Drive through front heel
  • Maintain balance and control

Unilateral work increases stability and muscle symmetry.

Exercise 4: Walking Lunges (Hypertrophy & Conditioning)

Sets: 3
Reps: 12 each leg
Rest: 45–60 seconds

Walking lunges improve coordination, endurance, and muscle size.

Focus on:

  • Long step for glute emphasis
  • Upright torso for quad focus

Exercise 5: Leg Curl or Stability Ball Curl

Sets: 3
Reps: 12–15
Rest: 45 seconds

This isolates hamstrings after compound lifts.

Control both concentric and eccentric phases for maximum hypertrophy.

Exercise 6: Standing Calf Raises

Sets: 3
Reps: 15–20
Rest: 30–45 seconds

Pause at the top for 1–2 seconds to fully contract calves.

Optional 5-Minute Finisher (Fat Burning Boost)

If time allows, finish strong:

Bodyweight Squat Jumps – 30 sec
Mountain Climbers – 30 sec
Alternating Reverse Lunges – 30 sec
(Rest 30 sec and repeat twice)

This boosts heart rate and increases metabolic output.

Weekly 45 Minutes Lower Body Workout Progression Strategy

To build muscle and strength, apply progressive overload.

Options:

  • Add 5–10 lbs weekly
  • Increase reps within range
  • Slow tempo
  • Reduce rest periods

Track your lifts weekly.

Tempo & Time Under Tension

For hypertrophy:

  • 2 seconds lift
  • 3 seconds lowering
  • Controlled movement

Increasing time under tension stimulates more muscle fibers.

Common Lower Body Training Mistakes

1. Skipping Warm-Ups

Leads to injury and weak performance.

2. Not Squatting Deep Enough

Limits quad and glute activation.

3. Ignoring Hamstrings

Creates muscle imbalances.

4. Using Too Much Weight

Compromises form and reduces effectiveness.

Nutrition Tips for 45 Minutes Lower Body Workout Leg Day Growth

To support this 45 minute lower body workout:

  • Consume protein (0.7–1g per lb bodyweight daily)
  • Eat carbs pre-workout for energy
  • Stay hydrated
  • Get 7–9 hours of sleep

Leg workouts demand fuel.

Who Should Use This 45 Minute Lower Body Workout?

This plan is ideal for:

  • Busy professionals
  • Intermediate lifters
  • Athletes
  • Fat loss programs
  • Hypertrophy training phases

Beginners can reduce weight and sets.

Can You Do This 45 Minutes Lower Body Workout at Home?

Yes. Modify with:

  • Dumbbells instead of barbell
  • Resistance bands for curls
  • Bodyweight calf raises
  • Backpack loaded with books

The structure stays the same.

How Often Should You Train Legs?

For optimal growth:

  • 1–2 dedicated leg days per week
  • At least 48 hours recovery
  • Combine with upper body split

Consistency drives results.

Sample 45 Minutes Lower Body Workout Weekly Split Example

  • Monday – Upper Body
  • Tuesday – Lower Body (This Workout)
  • Thursday – Upper Body
  • Friday – Lower Body Variation

Build Powerful Legs With 45 Minutes Lower Body Workout

A well-designed 45 minute lower body workout can produce serious gains when executed with intensity and consistency. Focus on compound lifts, control your tempo, and progressively overload your movements.

Train hard. Recover smart. Fuel your body.

Strong legs build a strong physique—and this workout gives you everything you need to get there.

For more leg-focused training inspiration and programming to complement your 45 minute lower body workout, be sure to explore additional resources on MensFitClub.com that dive deeper into effective routines and exercises. If you’re looking to expand your strength training foundation beyond this session, our Best Lower Body Workout Program For Men breaks down structured phases for different experience levels. For a broader selection of muscle-building routines, check out our collection of Men’s Fitness Workout Routines and Exercises, which includes leg-centric options alongside full body plans. If time-efficient training is your priority, the 30 Minute Lower Body Functional Workout to Build Strength offers an equipment-optional alternative that targets the same muscle groups. Want to diversify your leg days with fat-burning intensity? Visit the Best Lower Body Fat Burning Workout to Tone Legs & Glutes for a HIIT-style approach.

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    Men’s Fit Club was started with the goal of empowering men to get the most out of their lives. This meant going beyond exercise and diet tips to really address the broad range of issues that men face on a daily basis – topics like recreation, finding love, sexual health and even sound fashion advice.